Comparison Of The Effect Of Two-dose And One-dose Dexamethasone On Post-inflammatory Complications In Third Molar Surgery

Authors

  • AM Adetayo
  • TA Oyedele
  • AO Ajomoko
  • MO Adetayo
  • MO Adeyemi
  • MS Somoye
  • MO Gbotolorun

DOI:

https://doi.org/10.38029/bumj.v2i1.2

Abstract

Objective: This study aimed to compare the effects of administration of both preoperative and postoperative dexamethasone with that of only preoperative dexamethasone, and with that of a no dexamethasone (control) on reduction of pain, trismus and swelling following lower impacted 3rd molar surgery.

Methods: A prospective randomized controlled double blinded study at the dental clinic of Babcock University Teaching Hospital on 84 subjects that were divided into 3 groups. Group A had both preoperative and postoperative dexamethasone, while group B had only preoperative dexamethasone and group C was a 'no dexamethasone' group. Differential mean facial swelling, mouth opening and pain scores were compared within the three groups.

Results: The pattern of postoperative swelling, pain and trismus showed a general decrease from day 1 to 7, with group A showing the highest rate of decrease. On postoperative day 1, there was a difference between the swelling of groups A and C (p =0.01) and groups B and C (p = 0.02) and also between the pain scores of group A and group C (p = 0.01). On postoperative day 3, there was only a difference between the swelling of groups A and C (p = 0.02), but not in pain and trismus and no difference was seen in all the measured variables on postoperative day 7.

Conclusion: Administration of a combination of both preoperative and post operative dexamethasone to reduce the postoperative inflammatory sequelae that follows lower third molar surgery gave better results than administration of only a single preoperative dose.

Author Biographies

AM Adetayo

Department of Surgery, Benjamin Carson Snr School of medicine, Babcock University, Ilisan-Remo, Ogun State.

Dental Unit, Babcock University Teaching Hospital, Ilisan-Remo, Ogun State

TA Oyedele

Department of Surgery, Benjamin Carson Snr School of medicine, Babcock University, Ilisan-Remo, Ogun State.

Dental Unit, Babcock University Teaching Hospital, Ilisan-Remo, Ogun State

AO Ajomoko

Dental Unit, Babcock University Teaching Hospital, Ilisan-Remo, Ogun State

MO Adetayo

Department of Biological Sciences, Babcock University High School, Ilisan-Remo, Ogun State

MO Adeyemi

Oral & Maxillofacial Surgery, Lagos University Teaching Hospital, Idi-araba, Surulere, Lagos State

MS Somoye

Oral & Maxillofacial Surgery, Lagos University Teaching Hospital, Idi-araba, Surulere, Lagos State

MO Gbotolorun

Oral & Maxillofacial Surgery, Lagos University Teaching Hospital, Idi-araba, Surulere, Lagos State

Published

2017-09-30

How to Cite

Adetayo, A., Oyedele, T., Ajomoko, A., Adetayo, M., Adeyemi, M., Somoye, M., & Gbotolorun, M. (2017). Comparison Of The Effect Of Two-dose And One-dose Dexamethasone On Post-inflammatory Complications In Third Molar Surgery. Babcock University Medical Journal (BUMJ), 2(1), 8-17. https://doi.org/10.38029/bumj.v2i1.2

Issue

Section

Research Article